Funded Projects at CORE in 2011-2012
- CAP (Community Awareness Program) received funding from Blue Cross Blue Shield of Illinois, Grant Healthcare Foundation, Michael Reese Health Trust and Polk Bros. Foundation to support rapid testing and prevention education in the community.
- Project CONNECT is a one year pilot project promoting access to care funded by the Searle Funds at The Chicago Community Trust.
- DIFFA (Design Industries Foundation Fighting AIDS) recognized the Center’s contributions in providing quality HIV/AIDS care services for the fifth consecutive year. Funding will support the Center’s Case Management Self-Care Educational Series.
- Funding awarded by the Chicago Department of Public Health will support prevention services for people at risk for HIV infection and living with HIV. Funded projects include: CHAT (Community HIV/AIDS Talk), WHAT (Women HIV/AIDS Talk) and Project LEN (Link-Engage-Notify).
- Project HAT (HIV Accessible Testing) is funded through Gilead’s HIV FOCUS program
The CORE Center is committed to providing leadership in infectious disease research to help patients live longer, more comfortably and more independently. The performance of high quality research is central to the CORE Center’s mission, and the Research Department has broad experience with HIV research. Clinical research, behavioral science research and natural history studies are available to our patients, including pregnant women, children and adolescents. We conduct innovative and scientific studies that are patient-sensitive, using established methods and ethical principles. Research is designed and conducted to find better treatments for our patients and to improve our understanding of infectious diseases. This may involve new medications, vaccines, interviews and therapies. All studies are voluntary and available at no cost.
Developmental Center for AIDS Research
In 2009 NIH funded the Chicago Developmental Center for AIDS Research (D-CFAR). The CORE Center/Stroger Hospital is collaborating with Rush University Medical Center and the University of Illinois Chicago (UIC) in this five year program. The Clinical Core section of the D-CFAR is housed at the CORE Center under the direction of Audrey French, MD. One of the aims of the Clinical Core is to increase the depth and breadth of translational research by facilitating collaborations between researchers. Research interest groups established and supported by the Clinical Core include, HIV in Women, Drug Abuse and HIV, and HIV and Aging. Five CORE Center researchers have been awarded DCFAR pilot grants over the past three years for projects which vary from expanded HIV testing, intimate partner violence, resistant bacteria among HIV-infected persons, disparities in HIV diagnosis, to community factors which influence HIV outcomes. For additional information please go to: http://chicagocfar.org
Rush Center for Excellence on Disparities in HIV and Aging (CEDHA)
Funded in 2012, this 5-year NIH funded Program Project (P-20) is to build infrastructure through a partnership between Rush Aging/Alzheimer’s Center and the CORE Center. Lisa Barnes, PhD (Rush) is the Principal Investigator and Oluwatoyin Adeyemi, MD (CORE) is the co-leader of the Research Core. The CORE Center will be recruiting 175 HIV-infected individuals age 50 and older to participate in a 5-year longitudinal study that will include annual visits. The study will investigate how HIV influences the aging process.
Women’s Pathogenesis P-01: HIV Susceptibility Transmission in the Female Genital Tract
This NIH-funded project is a collaboration with Rush University Medical Center, University of Illinois Chicago, Northwestern University Medical Center and Rwanda investigators exploring factors in the female genital tract that influence HIV acquisition.
AIDS Malignancy Clinical Trials Consortium (AMC)
The AMC is a National Cancer Institute-supported clinical trials group that supports innovative trials for AIDS-related cancers. AMC working groups deal with the cancers that affect HIV-positive patients including Kaposi’s sarcoma, Lymphoma, Human Papillomavirus-related Cancers and Non-AIDS Defining Cancers (such as lung and liver cancer). In 2011 Stroger Hospital/CORE Center joined the AMC as an affiliate clinical trials site, one of two in Illinois. We currently have protocols open for Kaposi ’s sarcoma and Lymphoma. For more information visit the AMC website at http://pub.emmes.com/study/amc/public/index.htm
Major NIH Funded Studies at the CORE Center
Adolescent Trials Network
The Division of Adolescent Medicine at Stroger Hospital of Cook County Hospital is an Adolescent Medicine Trials Unit (ATU) in the Adolescent Medicine Trials Network (ATN) established by the National Institute of Child Health and Human Development. Our ATU conducts research that may improve the lives of 1) youth at risk of becoming infected with HIV and other infections like hepatitis A and B; and /or 2) youth who are already infected through better treatment methods. The adolescent research team is now working with the international team of investigators on the Pre-Exposure Prophylaxis Initiative (iPrEx).
For additional information contact the Project Coordinator at (312) 572-4571 or (312) 572-4554.
International Maternal, Pediatric, Adolescent AIDS Clinical Trials (IMPAACT)
The IMPAACT mission is to evaluate treatment for perinatally HIV-infected children and adolescents and pregnant women, including prevention of co-infections and co-morbidities. This study group conducts trials of novel pharmaceutical and immune therapies, vaccines and strategies for best use of existing antiretroviral medications in perinatally infected children.
For additional information contact the Project Coordinator at (312) 572-4541
Multicenter AIDS Cohort Study (MACS)
MACS is a prospective study of the natural and treated histories of HIV-1 infection in men who have sex with men conducted by sites located in Baltimore, Chicago, Pittsburgh and Los Angeles. Almost seven thousand men have been enrolled since its inception in 1984. The CORE Center site started enrollment in January, 2002 and has a cohort of over 80 men. This site augments research efforts in the long term benefits and adverse effects of therapy on men of color. Current sub-studies include cardiovascular, hepatitis B and pharmacokinetics research. For additional information contact the Project Coordinator at (312) 572-4552 or visit the national website at http://www.statepi.jhsph.edu/macs/macs.html.
Women’s Interagency HIV Study (WIHS)
WIHS was established in August 1993 to investigate the impact of HIV infection on women in the United States. The WIHS has sites in six major U.S. cities including Chicago, Brooklyn, the Bronx, San Francisco, Los Angeles and Washington, D.C. Over 3000 women have enrolled in the WIHS nationally, including over 400 women here in Chicago. The extraordinary commitment of WIHS participants, who participate in two research visits every year including complete physical and gynecological exams, laboratory testing and a detailed interview about their health, makes it possible to learn more about the physical, emotional and social health of HIV positive women in the U.S. The Chicago WIHS program includes patients from other area hospitals including Northwestern Memorial Hospital, Rush University Medical Center, and University of Illinois at Chicago Hospital.
For additional information please visit the national WIHS website at http://statepiaps.jhsph.edu/wihs/
Adult Clinical Trials
The adult clinical trials program includes industry-sponsored and investigator-initiated studies. Please contact the coordinator at (312) 572-4543 to learn what trials are currently open for enrollment.